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KMID : 0380020050200050387
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Korean Journal of Biotechnology and Bioengineering
2005 Volume.20 No. 5 p.387 ~ p.391
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Analysis of Conservative Genes in Thermophilic and Hyperthermophilic Bacteria
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Lee Dong-Geun
Lee Jae-Hwa
Ha Bae-Jin
Ha Jong-Myuong
Lee Jung-Hyun
Kim Sang-Jin
Lee Sang-Hyun
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Abstract
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Totally 16,299 conservative genes, commonly found in 13 thermophilic and hyperthermophilic bacteria, were analyzed. All genes were belong to W 67 COGs (clusters of orthologous groups of proteins). COGs related to protein metabolism were 80 among 167 COGs. Conservative genes were not limited only thermophiles and hyperthermophiles, meaning thermal stability is independent of specific protein. However reverse gyrase was only found in all hyperthermophilic archaebacteria and eubacteria, meaning DNA stability is important in hyperthermophiles. Hyperthermophilic eubacteria and thermophilic archaebacteria had different position between phylogenetic tree of gene content and 165 rRNA gene. Thermophilic archaebacteria hyperthermophilic eubacteria and archaebacteria had similar values by the statistical analysis of distance values with 167 COGs in each organism.
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KEYWORD
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Thermophiles, hyperthermophiles, 16S rRNA, gene content tree, COG, clusters of orthologous groups of proteins
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